Alzheimer's disease

Dr. Michael Duplessie, FRCS Ophth (Glasgow), M.B., B.Ch., L.R.C.P. & S.I., B.A.O., B.A.


Alzheimer’s disease (AD) is a neurological disorder that gradually diminishes cognitive abilities and neuronal function. The existing treatments for AD demonstrate effectiveness solely during the initial stages of the ailment. The complete understanding of the origins and ramifications of AD remains an ongoing quest, making the pursuit of novel approaches to treat this affliction of utmost significance.

Cannabinoids, renowned for their recreational and pharmacological properties, have been known for centuries. Recently, the scientific community has embarked upon an exploration of the potential employment of cannabinoids in AD therapy, yielding occasionally contradictory outcomes. The endocannabinoid system (ECS) exhibits significant expression within the hippocampus and cortex, instigating concerns regarding the potential cognitive impairment and learning dysfunction in vulnerable individuals stemming from cannabis usage or abuse.

Nevertheless, recent discoveries in AD rodent models indicate that cannabinoids hold promise in diminishing amyloid plaque accumulation and promoting hippocampal neurogenesis. Clinical trials have also reported favorable effects on various symptoms related to dementia subsequent to cannabinoid treatments. Thus, forthcoming studies should concentrate on identifying the optimal therapeutic dosage and timing of administration to maximize the advantages derived from implementing cannabinoids in AD therapy.

In summary, although the utilization of cannabinoids for AD therapy remains in its nascent stages, the latest research instills hope for the development of effective and secure medications. The path forward may be arduous, but through continued scientific investigation, a solution to combat this devastating disease may eventually be found.

Medical Marijuana

Safe & Legal

Throughout my career, I have been dedicated to breaking conventions and helping those in need. My passion for medicine began during my time working in refugee camps in Thailand, and since then, I have made it my mission to provide care and support to those who need it most.

As a pioneer in the field of ophthalmology, I have made numerous contributions and innovations in the field of corneal transplantation and laser surgery.  I am comfortable challenging conventions.

I have seen firsthand the positive impact medical marijuana can have on patients struggling with pain and anxiety. 

My experiences have shown me that medical marijuana can offer significant benefits with minimal side effects, providing patients with an alternative to traditional pharmaceutical medications. Despite its potential, the government’s stance on marijuana is outdated and in need of revision. 

Through my observations, I have seen prescription rates for pain, stress, insomnia, anxiety to name just a few, drastically decrease among patients who have obtained a medical marijuana card, and I believe that this is a testament to its effectiveness.

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Experienced Physician

Pioneer and Leader

Personalized Patient Care

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Dr. Duplessie is offering telemedicine visits in:

 New York, Ohio, Pennsylvania & Virginia