Amblyopia, Strabismus are terms for a condition that is also sometimes called lazy eye. 


Amblyopia is a neuro-developmental disorder involving a decrease in visual acuity that cannot be explained by ocular abnormalities. 

It affects 2-3% of the population and is the prevalent cause of monocular [one eye] blindness


The brain and the eyes work together to produce vision. The eye focuses light on the back part of the eye known as the retina. Cells of the retina then trigger nerve signals that travel along the optic nerves to the brain. Amblyopia is the medical term used when the vision of one eye is reduced because it fails to work properly with the brain. The eye itself looks normal, but for various reasons the brain favors the other eye.

How common is amblyopia?

Amblyopia is the most common cause of visual impairment among children, affecting approximately 2 to 3 out of every 100 children. Unless it is successfully treated in early childhood, amblyopia usually persists into adulthood. It is also the most common cause of monocular (one eye) visual impairment among young and middle-aged adults.



Causes of Amblyopia:



What causes amblyopia?  Amblyopia can result from any condition that prevents the eye from focusing clearly. Amblyopia can be caused by the misalignment of the two eyes—a condition called strabismus. With strabismus, the eyes can cross in (esotropia) or turn out (exotropia).



Glasses will treat if not cure a strabismus problem called Accommodative esotropia




Other Causes of Amblyopia


Occasionally, amblyopia is caused by a clouding of the front part of the eye, a condition called cataract.




A common cause of amblyopia is the inability of one eye to focus as well as the other one. Aniseikonia is an ocular condition where there is a significant difference in glasses prescription between the eyes.  Objects are seen as bigger or smaller in different eyes.  Glasses reduce  the different perception of size of images.

Lazy eye or Amblyopia can occur when one eye is more nearsighted, more farsighted, or has more astigmatism.



Farsightedness, or hyperopia,

occurs when the distance from the front to the back of the eye is too short.

Eyes that are farsighted tend to focus better at a distance but have more difficulty focusing on near objects.

Nearsightedness, or myopia,

occurs when the eye is too long from front to back. Eyes with nearsightedness tend to focus better on near objects.





The eyes have difficulty focusing on far and near objects because of their irregular shape.



Amblyopia, Strabismus, Lazy Eye, Treatment Options:



How is amblyopia treated in children?

Amblyopia is a neurodevelopmental disorder that cannot be corrected by optical means, though wearing the correct prescription is a vital part of the treatment strategy. Treating amblyopia involves forcing the child to use the eye with weaker vision.



There are two common ways to treat amblyopia:






An adhesive patch is worn over the stronger eye for weeks to months. This therapy forces the child to use the eye with amblyopia. Patching stimulates vision in the weaker eye and helps parts of the brain involved in vision develop more completely.


 A recent study showed that patching the unaffected eye of children with moderate amblyopia for two hours daily works as well as patching for six hours daily. Shorter patching time can lead to better compliance with treatment and improved quality of life for children with amblyopia. However, a recent study showed that children whose amblyopia persists despite two hours of daily patching may improve if daily patching is extended to 6 hours.

Previously, Ophthalmology researchers thought that treating amblyopia would be of little benefit to older children. However, results from a nationwide clinical trial showed that many children from ages seven to 17 years old benefited from treatment for amblyopia. This study shows that age alone should not be used as a factor to decide whether or not to treat a child for amblyopia.

Eye Drops instead of patching for the treatment of Amblyopia

A drop of a drug called atropine is placed in the stronger eye to temporarily blur vision so that the child will use the eye with amblyopia, especially when focusing on near objects. Research has shown that atropine eye drops, when placed in the unaffected eye once a day, work as well as eye patching.



Atropine eye drops are sometimes easier for parents and children to use.


Amblyopia, Strabismus, Lazy Eye, Treatment Options.  Can amblyopia be treated in adults?

Patching of the amblyopic eye is a powerful treatment in early childhood but its effectiveness decreases with age, which has been attributed to decreased plasticity in the adult brain.

During the first seven to ten years of life, the visual system develops rapidly. Important connections between the eye and the brain are created during this period of growth and development. Recent work has suggested there may be some benefit.

Adult patients benefit from corrective surgery for ocular misalignment, but also for social anxiety levels associated with improvements in their quality of life and disability levels.