Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease

Dr. Michael Duplessie, FRCS Ophth (Glasgow), M.B., B.Ch., L.R.C.P. & S.I., B.A.O., B.A.

Amyotrophic lateral sclerosis (ALS)


People with multiple sclerosis (MS) have long resorted to self-medicating, whether with illegal street cannabis or the more recent introduction of medicinal cannabis, to alleviate the symptoms linked to MS and amyotrophic lateral sclerosis (ALS). Numerous anecdotal reports supporting these claims have found validation through data obtained from animal models and, more recently, clinical trials exploring the impact of cannabinoids on limb spasticity—a common manifestation of progressive MS and ALS—as well as neurodegeneration.

Through experimental studies delving into the intricacies of the endocannabinoid system, we have unveiled the manifold efficacy of cannabinoids. Not only do they offer relief from symptoms, but they also demonstrate potential as neuroprotective agents, capable of impeding disease progression and delaying symptom onset. In this comprehensive review, we delve into our current understanding of the endocannabinoid system’s interplay with MS and ALS, shedding light on the therapeutic prospects of cannabinoid treatments as agents for modifying disease progression or symptom control. Moreover, we explore future therapeutic strategies, including their potential in decelerating the advancement of MS and ALS.

Medical Marijuana

Safe & Legal

Throughout my career, I have been dedicated to breaking conventions and helping those in need. My passion for medicine began during my time working in refugee camps in Thailand, and since then, I have made it my mission to provide care and support to those who need it most.

As a pioneer in the field of ophthalmology, I have made numerous contributions and innovations in the field of corneal transplantation and laser surgery.  I am comfortable challenging conventions.

I have seen firsthand the positive impact medical marijuana can have on patients struggling with pain and anxiety. 

My experiences have shown me that medical marijuana can offer significant benefits with minimal side effects, providing patients with an alternative to traditional pharmaceutical medications. Despite its potential, the government’s stance on marijuana is outdated and in need of revision. 

Through my observations, I have seen prescription rates for pain, spasticity, stress, insomnia, anxiety to name just a few, drastically decrease among patients who have obtained a medical marijuana card, and I believe that this is a testament to its effectiveness.

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Experienced Physician

Pioneer and Leader

Personalized Patient Care

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Dr. Duplessie is offering telemedicine visits in:

 New York, Ohio, Pennsylvania & Virginia