Medical marijuana for inflammatory bowel disease

Dr. Michael Duplessie, FRCS Ophth (Glasgow), M.B., B.Ch., L.R.C.P. & S.I., B.A.O., B.A.

IBD – Inflammatory bowel disease: 

The potential use of cannabis in the treatment of inflammatory bowel disease (IBD) has gained interest from patients seeking alternatives to conventional therapies and relief from refractory disease. Although data have shown its potential role in pain reduction, its impact on the underlying inflammatory process of IBD remains unclear.

This review aims to summarize the current literature on cannabis as a treatment for IBD and identify potential areas for future research. While cannabis holds promise as a supportive medication for IBD, additional research is necessary to determine its efficacy and safety as a treatment option.

Inflammatory bowel disease (IBD) affects millions of people worldwide, causing debilitating symptoms that can significantly reduce their quality of life. While conventional treatments can alleviate some symptoms, many patients continue to suffer from refractory disease, prompting increased interest in alternative therapies such as cannabis-based medicinal products (CBMPs).

While preclinical studies have shown promising results for CBMPs in IBD, clinical trials have not consistently demonstrated effects on inflammation. Nonetheless, recent analysis from the UK Medical Cannabis Registry indicates that CBMPs may have a positive impact on patients’ health-related quality of life (HRQoL).

Specifically, this case series study included 76 IBD patients prescribed CBMPs, with improvements in their SIBDQ, GAD-7, SQS, and EQ-5D-5L Index scores observed at 1 and 3 months. Adverse events were reported in a small percentage of patients, but they were generally mild to moderate in severity.

While further research is necessary to fully understand the effects of CBMPs on IBD, these findings offer hope for patients seeking relief from refractory symptoms. Those who have prior experience with cannabis may benefit even more. With continued investigation, CBMPs could become a viable treatment option for those with IBD.

Medical Marijuana

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Throughout my career, I have been dedicated to breaking conventions and helping those in need. My passion for medicine began during my time working in refugee camps in Thailand, and since then, I have made it my mission to provide care and support to those who need it most.

As a pioneer in the field of ophthalmology, I have made numerous contributions and innovations in the field of corneal transplantation and laser surgery.  I am comfortable challenging conventions.

I have seen firsthand the positive impact medical marijuana can have on patients struggling with pain and anxiety. 

My experiences have shown me that medical marijuana can offer significant benefits with minimal side effects, providing patients with an alternative to traditional pharmaceutical medications. Despite its potential, the government’s stance on marijuana is outdated and in need of revision. 

Through my observations, I have seen prescription rates for pain, stress, insomnia, anxiety to name just a few, drastically decrease among patients who have obtained a medical marijuana card, and I believe that this is a testament to its effectiveness.

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