Pain: Chronic Pain

Dr. Michael Duplessie, FRCS Ophth (Glasgow), M.B., B.Ch., L.R.C.P. & S.I., B.A.O., B.A.

Pain: Cannabis and Cannabinoids for Chronic Pain

Chronic pain is a debilitating condition that affects millions of people worldwide. While conventional treatments offer some relief, they are not always effective, and can have severe side effects. In recent years, the potential of cannabis and cannabinoids as a treatment for chronic pain has garnered attention, with many patients reporting significant improvement in their symptoms.

An up-to-date review of the scientific evidence on the analgesic effects, safety, and tolerability of cannabis and cannabinoids for chronic pain:  

Findings suggest that:

  1. Inhaled cannabis, whether smoked or vaporized, is consistently effective in reducing chronic non-cancer pain.
  2. Oral cannabinoids show promise in improving some aspects of chronic pain, such as sleep and quality of life, but are not effective for acute postoperative pain, abdominal chronic pain, or rheumatoid pain.
  3. While inhaled cannabis is generally more tolerable and predictable than oral cannabinoids, it is important to note that cannabis and cannabinoids are not universally effective for pain.
  4. Continued research is needed to explore the efficacy of cannabis constituents and improve the bioavailability of oral cannabinoids.


Other aspects of pain management in patients using cannabis require further discussion, including concomitant opioid use, medical versus recreational cannabis, and abuse potential. Nonetheless, the potential of cannabis and cannabinoids as a treatment for chronic pain offers hope for individuals seeking alternative therapies. As research in this area continues, it is possible that cannabis and cannabinoids may prove to be valuable additions to the pain management toolkit.

Medical Marijuana

Safe & Legal

Throughout my career, I have been dedicated to breaking conventions and helping those in need. My passion for medicine began during my time working in refugee camps in Thailand, and since then, I have made it my mission to provide care and support to those who need it most.

As a pioneer in the field of ophthalmology, I have made numerous contributions and innovations in the field of corneal transplantation and laser surgery.  I am comfortable challenging conventions.

I have seen firsthand the positive impact medical marijuana can have on patients struggling with pain and anxiety. 

My experiences have shown me that medical marijuana can offer significant benefits with minimal side effects, providing patients with an alternative to traditional pharmaceutical medications. Despite its potential, the government’s stance on marijuana is outdated and in need of revision. 

Through my observations, I have seen prescription rates for pain, stress, insomnia, anxiety to name just a few, drastically decrease among patients who have obtained a medical marijuana card, and I believe that this is a testament to its effectiveness.

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